2 resultados para animal models, neutrophils, platelets, sheep, TRALI, two-event

em Aquatic Commons


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I simulated somatic growth and accompanying otolith growth using an individual-based bioenergetics model in order to examine the performance of several back-calculation methods. Four shapes of otolith radius-total length relations (OR-TL) were simulated. Ten different back-calculation equations, two different regression models of radius length, and two schemes of annulus selection were examined for a total of 20 different methods to estimate size at age from simulated data sets of length and annulus measurements. The accuracy of each of the twenty methods was evaluated by comparing the back-calculated length-at-age and the true length-at-age. The best back-calculation technique was directly related to how well the OR-TL model fitted. When the OR-TL was sigmoid shaped and all annuli were used, employing a least squares linear regression coupled with a log-transformed Lee back-calculation equation (y-intercept corrected) resulted in the least error; when only the last annulus was used, employing a direct proportionality back-calculation equation resulted in the least error. When the OR-TL was linear, employing a functional regression coupled with the Lee back-calculation equation resulted in the least error when all annuli were used, and also when only the last annulus was used. If the OR-TL was exponentially shaped, direct substitution into the fitted quadratic equation resulted in the least error when all annuli were used, and when only the last annulus was used. Finally, an asymptotically shaped OR-TL was best modeled by the individually corrected Weibull cumulative distribution function when all annuli were used, and when only the last annulus was used.

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EXTRACT (SEE PDF FOR FULL ABSTRACT): Current projections of the response of the biosphere to global climatic change indicate as much as 50 to 90% spatial displacement of extratropical biomes. The mechanism of spatial shift could be dominated either by competitive displacement of northern biomes by southern biomes or by drought-induced dieback of areas susceptible to change. The current suite of global biosphere models cannot distinguish between these two processes, hence the need for a mechanistically based biome model. The first steps have been taken toward development of a rule-based, mechanistic model of regional biomes at a continental scale. ... The model is in an early stage of development and will require several enhancements, including: explicit simulation of potential evapotranspiration, extension to boreal and tropical biomes, a shift from steady-state to transient dynamics, and validation on other continents.